pacific dusk

A hypotensive effect, respiratory depression, a depressing effect on the nervous system is observed with the joint prescription of medicines that depress the central nervous system: general anesthetics, benzodiazepines, barbiturates, antidepressants and others.

There is a decrease in the effectiveness of alpha-blockers, phenytoin. Fluvoxamine, fluoxetine increase the concentration of the drug in the blood. The risk of developing epileptic seizures increases, and the central anticholiner...